Cosmetic Grade Hyaluronic Acid Powder CAS 9004-61-9 Hyaluronic Acid

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Product Name: Hyaluronic Acid Powder
• Shelf Life: 2 Year When Properly Stored
• Sample: Available
• Grade: Cosmetic Grade
• Storage: Cool and Dry Place
• Package: 25kgs/Drum or Carton, Inner by Aluminum Foil Bag
• Brand: Wh
• Produce Capacity: 500kg/Per Month
• Appearance: White Powder
• CAS: 9004-61-9
• Transport Package: Bag or Drum
• Origin: China
• Production Capacity: 100000000 Piece/Year

Product Description

 

What's Hyaluronic acid ?

· Hyaluronic acid is a mucopolysaccharide based on N-acetylglucosamine and glucuronic acid disaccharide repeated unit. Hyaluronic acid is widely presented in soft connective tissues of human and animals such as intercellular substance, vitreous body, umbilical cord, skin, joint synovia and cock' s comb.

· Its molucule weight range from tens of thousands to multi-million, main physiological function is moisture, lubrication and osmoregulation.

Product Description

·   With age, the body's HA decreases. Oral health products containing hyaluronic acid can supplement the body's HA, have the effects of delaying aging and moisturizing the skin, and have been widely used in Japan, the United States and other countries. Hyaluronic acid has been used in eye drops, surgical materials and injections in medicine.

1) increase skin elasticity, postpone skin aging.
2)promote the proliferation and differentiation of epidermal cells, removal of oxygen free radicals,
3)prevent and repair skin damage. Hyaluronic acid aqueous solution has high viscosity
4)make the water phase thickening; And paste evenly after the oil phase emulsification is exquisite, has the stable emulsification. Hyaluronic acid is one of the best natural moisturizing ingredients of high-end cosmetics, good compatibility
5)Can be added to almost any beauty cosmetics, widely used in cream, lotion, lotion, essence, cleansers, bath, wash hair, moss, expansion, lipstick and other cosmetics, general content is 0.05-0.5%.


1. Food Grade

2. Cosmetic Grade

3. Eyedrops Grade(Pharm Grade)

4. Injection Grade(Pharm Grade)

1. Food supplements:
Hyaluronic Acid through the oral administration after the digestion absorption, increases in vivo Hyaluronic Acid synthesis the precursor, causes in the skin and other organization's Hyaluronic Acid resultant quantity increases, thus enables the skin the water retention property to increase, rich elasticity, wrinkle reduction.
Hyaluronan through the oral administration after the digestion absorption, increases in vivo hyaluronan synthesis the precursor, causes in the skin and other organization's hyaluronan resultant quantity increases, thus enables the skin the water retention property to increase, rich elasticity, wrinkle reduction. 

Specification\Name	Food Grade Hyaluronic Acid
Characters	White or straw yellow powder
Hyaluronic Acid (dry basis)	90%-105%
Glucuronic acid	≥42.0%
PH(0.1% Water Solution)	6.0-8.0
Molecular Weight	(0.8-2.0)*106
Protein	≤ 0.1%
Transparency (0.1% Solution)	≥99%
Residue on Ignition	≤20
Loss on drying	≤10.0%
Heavy metals (as Pb)	≤ 20ppm
Arsenic	≤2ppm
Bacteria count	≤ 100CFU/g
Mold & Yeast	≤10CFU/g
Salmonella	Negative
Escherichia coli	Negative

2. Cosmetics applications:
Hyaluronic Acid has outstanding moisture keeping ability, thus called Natural Moisturing Factor in the world. Hyaluronic Acid is a common ingredient in skin-care products, which can be used as a very effective topical humectant, which can be used for facial wrinkles, reduction of folds and wrinkles, and removal of scars.
Hyaluronan has outstanding moisture keeping ability, thus called Natural Moisturing Factor in the world. Hyaluronan is a common ingredient in skin-care products, which can be used as a very effective topical humectant. In 2003, the FDA approved hyaluronan injections for filling soft tissue defects, which can be used for facial wrinkles, lip augmentation, reduction of folds and wrinkles, and removal of scars.

 

v
Items	Specifications
	Cosmetic Grade HA (Low Molecular Weight )	Cosmetic Grade HA (Middle Molecular Weight )	Cosmetic Grade HA (High Molecular Weight )
Characters	White or off-white powder	White or off-white powder	White or off-white powder
Hyaluronic Acid (dry basis)	90%-105%	90%-105%	90%-105%
PH(0.1% Water Solution)	6.0-7.5	6.0-7.5	6.0-7.5
Molecular Weight	10K Da - 1,000K Da	1,000K Da - 1,800K Da	≥1,800K Da
Glucuronic acid	≥45.0%	≥45.0%	≥45.0%
Protein	≤0.08%	≤0.08%	≤0.08%
Heavy metals (as Pb)	≤20ppm	≤20ppm	≤20ppm
Loss on drying	≤10.0%	≤10.0%	≤10.0%
Residue on Ignition	≤20	≤20	≤20
Bacteria count	≤100cfu/g	≤100cfu/g	≤100cfu/g
Mold & Yeast	≤10cfu/g	≤10cfu/g	≤10cfu/g
Salmonella	Negative	Negative	Negative
Escherichia coli	Negative	Negative	Negative

 

Application

 

1). Used in eye surgery, such as corneal transplantation, cataract surgery, glaucoma surgery, and surgery to repair retinal detachment.
 
2). Treat osteoarthritis of the knee. They are administered as a course of injections into the knee joint, which are believed to supplement the viscosity of the joint fluid, thereby lubricating the joint, cushioning the joint, and producing an analgesic effect.
 
3). Applied in the synthesis of biological scaffolds for wound-healing applications. These scaffolds typically have proteins such as fibronectin attached to the Hyaluronic Acid to facilitate cell migration into the wound.
 

Specification\Name	Eye Drop Grade Hyaluronic Acid
Characters	White hygroscopic powder or granule
Hyaluronic Acid (dry basis)	90%-105%
Glucuronic acid	≥45.0%
PH(0.1% Water Solution)	6.0-7.5
Molecular Weight	(0.8-2.0)*106
Intrinsic viscosity	≥1600(on the dries basis )
Residue on Ignition	≤20%
Protein	≤0.1%
Transparency (0.1% Solution)	≥99%
Loss on drying	≤8.0%
Heavy metals (as Pb)	≤ 20ppm
Arsenic	≤2ppm
Bacteria Endotoxin	≤0.5 EU/mg
Hemolysis	Negative
Viable Hemolytical Streptococci	Negative
Bacteria count	≤10CFU/g
Mold & Yeast	≤10CFU/g
Pseudomonas aeruginosa	Negative

 
Equine applications:
Hyaluronan is used in treatment of articular disorders in horses, in particular those in competition or heavy work. It is indicated for carpal and fetlock joint dysfunctions, especially used for synovitis associated with equine osteoarthritis. It can be injected directly into an affected joint, or intravenously for less localized disorders. It may cause mild heating of the joint if directly injected, but this does not affect the clinical outcome. Intra-articularly administered medicine is fully metabolized in less than a week.
 

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